Background: A nurse as a family planning Counselor helps women choose and use family planning methods that suit their needs. Nursing protocol improves nurses' knowledge and skill regarding family planning counseling which in turn helps in overcoming obstacles facing nursing counsellors Aim: assess the effect of nursing protocol on overcoming obstacles that face nurses during family planning counseling. Subject and Methods: A quasi-experimental research (pre/post-test) design; sampling: A purposive sample of 80 nurses at Ain Shams University Maternity Hospital in family planning clinics were recruited in the current study. Tools: Data was collected using 1) a Structured Interviewing Arabic questionnaire which included 3 parts nurses' demographic data, nurses' knowledge regarding family planning counselling and Obstacles facing nurses' during family planning counselling:2) observational checklist used for assessment of the quality of family planning counseling sessions. Results: 22.5% of nurses had good knowledge of pre-nursing protocol implementation which improved to 87.5% post-implementation. While 14.2% of nurses had good practice regarding family planning counseling compared to 74.2% post-implementation of the nursing protocol. Concerning obstacles that facing nurses' during family planning counseling the high obstacle was 35.0% pre-nursing protocol implementation which decreased to 22.5% post-implementation. Conclusion: the study concluded that the implementation of the nursing protocol has a positive effect on nurses' total knowledge, practice, and overcoming obstacles regarding family planning counseling. Recommendation: Implementation of nursing protocol at family planning clinic at different family planning services.