Background: Coronary artery disease (CAD) is major global concerns.CAD can cause more than 23 million deaths in 2030 around the world. Improvement of patients` life style practices are achieved by effective utilization of an educational program. Aim: This study aimed to evaluate the effect of implementing an educational program on life style practices among patients with CAD. Subjects and method: A Quasi-experimental design was utilized in this study. Setting: the study was conducted at the Intensive Care Units and Cardiac Outpatient Units in Suez Canal University Hospital, at Ismailia city. Subjects: A purposive sample of 70 patients was classified into two groups, the study (n=35) and the control (n=35).Tools: Data was collected through two tools, knowledge assessment regard CAD and clinical data tool and CAD patient practices and Life style tools. Results: It was observed that the total mean score of lifestyle practices among the study group was improved higher post implementation of educational program more than control group (230.29±5.81 compared to 199.77±9.49) Additionally, there was a negative statistical correlation p=0.0.Conclusion: the study results concluded that implementation of the educational program was associated with improvement in life style and practices for CAD patients. Recommendation: Promotion of self-care management to the CAD patients through simple exercise, monitoring nutrition habits, management of stress and follow up should be continued to improve life style.