Background: Knee osteoarthritis is one of the most frequent causes of physical disability among adult world wide. Aim of the present study was to evaluate effect of nursing care by using kinesio tape , swedish massage on knee osteoarthritis patients , pain , functional status and quality of life Subjects and method; A quasi-experimental study was conducted at the Physical Medicine, Rehabilitation and rheumatology Department of Tanta University Hospital. A convenience sampling of 100 adults patients was divided into four groups. Each consist of 25patients, group1 control groups and study groups 2, 3,4are the study groups. Tools: Three tools were used for data collection as follow; Tool (I) Structured interview Questionnaire included two parts Part (one) Bio sociodemographic data, Part (two): Physical Health Status Assessment , Tool (II)Pain assessment tool, Tool (III) Tool :Short Form 36 (SF-36) Health Survey Questionnaire. Results; the main results revealed that there was statistical significant improvement in functional status study group4 (swedish massage, kinesio tapimg) than other three groups(1,2,3) throughout the intervention period of the study and There was a high statistical significant improvement in quality of life for study group4 (swedish massage, kinesio taping) than other three groups(1,2,3) throughout the intervention period of the study. Conclusion and recommendations: Swedish massage and kinesiology taping had positive effect on reduction of pain and improving , functional status and quality of life .encouraging for combination of kinesio tape ,Swedish massage with other treatments as core treatment for kneeosteoarhritis patients