Background: Coronavirus disease 2019 is a serious respiratory disease that is caused by a novel severe acute respiratory syndrome coronavirus 2. Understanding health-related quality of life (HRQOL) of hospitalized COVID-19 survivors is an emerging global challenge arising from the current pandemic. Aim: This study aimed to assess health related quality of life for patients post coronavirus (COVID-19) pandemic. Design: A prospective research design was used to achieve the aim of this study. Setting: This study was conducted at medical outpatients clinic affiliated to Helwan General Hospital. Sample: A purposive sample of 100 recently recovered patients post COVID-19 from the selected setting was included in the study. Tools: two tools were used in this study; Patients structured Interview Questionnaire, Euro Quality of life 5-dimensions questionnaire (EQOL-5D). Results: The majority of post COVID-19 patients had a history of chronic diseases and a contact with COVID-19 patient. The most common symptoms at admission were hyperthermia, dry cough, dyspnea, nausea and vomiting. After discharge, majority of studied patients complain of fatigue, joint pain, myalgia, headache, and anxiety. More than half of them reported some problems in walking; performing usual activities and moderate pain or discomfort. Conclusion: There were statistically significant relations between history of chronic disease and total QOl scores, as well as, between physical and psychological complications post COVID 19 and total QOl scores. Recommendations: Healthcare workers should pay more attention to physical and psychological rehabilitation of discharged COVID-19 patients.