The aim of the present study is to evaluate sexual and psychological effects of female genital mutilation (circumcisin ). This was a case control and comparative study that was conducted at obstetrics and gynecology outpatient clinic at Beni-Suef University Hospital, Beni-Suef, Egypt. This study included 96 sexually active females who were classified into two groups: Group (1): Included 48 sexually active who were subjected to FGM/C, and Group (2): Included 48 sexually active who weren't subjected to FGM/C. The females within the two groups showed significant difference in their satisfaction with the process and subsequently in their future decision in performing circumcision for their daughters. Female genital mutilation (FGM) didn't affect the overall sexual functions as assessed by Female Sexual Function Index (FSFI) questionnaire except for the lubrication and orgasm domains. . We concluded that Female genital mutilation (circumcision) (FGM/c) is still common in Egypt inspite of efforts for panning of the process. Female genital mutilation (FGM) didn't reveal a significant effect on the development of anxiety and depression.