Cardiac resynchronization therapy (CRT) has become an important treatment strategy for a select group of heart failure (HF) patients, few studies have examined the optimal basal atrial pacing rate and its impact on long-term outcome in CRT patients. 30 CRT patients were divided to two groups and programmed to 70 – 80 bpm basal atrial pacing rates respectively for 6 months with comparing the effect of each programming on the quality of life using Minnesota heart failure questionnaire and echocardiographic findings ( EF, LVEDD , LVESD , LVEDV, LVESV ). There was a highly significant difference between both groups as group 2 (with basal heart rat=80) had higher MFHQ after the programming with mean=67.2 ±9.1 vs group 1 (with basal heart rate =70) with mean 50.6 ±8.3 (P-value<0.001).Also, there was no significant effect of the programming on NYHA of group I (P-value=0.301) but, the programming increase the NYHA of group II significantly (P-value=0.014). The programming didn't affect the (EF, LVEDD, LVESD, LVEDV, LVESV) of both groups significantly (p-value = 0.916, 0.786 for both groups). The lower basal trial pacing rate the better quality of life and the lower NYHAclass.