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89074

Use of phytoestrogen with clomiphene citrate for ovulation induction in polycystic ovary syndrome

Article

Last updated: 22 Jan 2023

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Abstract

The goal of this study is to assess the effectiveness of phytoestrogen with clomiphene citrate for ovulation induction in women with polycystic ovarian syndrome to overcome the antiestrogenic effect of clomiphene citrate on endometrium, were randomly grouped into two groups, 50 in each group. Group 1: receiving CC 100 mg twice daily from third day of cycle for five days and group 2:  receiving CC from 3rd of cycle for 5 days plus phytoestrogen (Klimadynon(®), Bionorica, Neumarkt i.d.OBf., Germany)  (20mg of cimifuga racemosa from day 1to12). Women receiving CC plus phytoestrogen have an increase number of dominant follicles, endometrial thickness with an improvement of both ovulation rate and pregnancy rate.

DOI

10.21608/ejmr.2020.89074

Keywords

Cimicifuga, Clomiphene citrate, Endometrial Thickness, Induction, Phytoestrogens

Authors

First Name

Mohamed

Last Name

Mehasen

MiddleName

Nagi

Affiliation

Obstetrics and Gynecology department, Faculty of Medicine, Cairo University, Egypt

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Orcid

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First Name

Eman

Last Name

Farid

MiddleName

Zein Elabdeen

Affiliation

Obstetrics and Gynecology department, Faculty of Medicine, Beni-Suef University, Egypt

Email

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City

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Orcid

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First Name

Ahmed

Last Name

Maged

MiddleName

-

Affiliation

Obstetrics and Gynecology department, Faculty of Medicine, Beni-Suef University, Egypt

Email

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City

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Orcid

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First Name

Azhar

Last Name

Farid

MiddleName

-

Affiliation

Obstetrics and Gynecology department, Faculty of Medicine, Beni-Suef University, Egypt

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City

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Orcid

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Volume

1

Article Issue

1

Related Issue

13387

Issue Date

2020-01-01

Receive Date

2020-05-13

Publish Date

2020-01-01

Page Start

91

Page End

105

Print ISSN

2682-4396

Online ISSN

2682-440X

Link

https://ejmr.journals.ekb.eg/article_89074.html

Detail API

https://ejmr.journals.ekb.eg/service?article_code=89074

Order

8

Type

Original Article

Type Code

1,224

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Research

Publication Link

https://ejmr.journals.ekb.eg/

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Article

Created At

22 Jan 2023