Background: Vitiligo is an acquired depigmentary skin disease that manifests as circumscribed depigmented patches or macules on the skin. It may have devastating psychological and social consequences Vitiligo is a common depigmenting disorder with profound psychosocial impacts. Although the etiology of vitiligo remains obscure, recent experimental studies infer the presence of interactions between melanocytes and other typical skin cells, particularly keratinocytes. Patients and methods: This study investigated the demographic data in 30 vitiligo patients at the dermatology department in Beni-Suef University Hospital. Results: The most significant findings in the clinical data were as follow: the female number doubled that of males, 46.7% of patients were housewives, negative family history of vitiligo was in 85.7% of patients, the commonest type of vitiligo was the Vulgaris (50.0%), 70% of patients had skin type VI, 80% of patients had a generalized form of the disease, 96.7% had bilateral disease, and 50 % of the biopsies were taken from the back. Conclusion: This was an epidemiologic study of patients with psoriasis in Egypt and provides an overview of the epidemiologic characteristics and clinical profiles of this patient population.