Diabetes has been considered one of the most prevalent diseases. It has also posed a great threat to the health of many groups of people. Likewise, it negatively affects the body's organs causing many changes and problems, such as; skin problems, especially bacterial and fungal skin infections.To the end of ensuring a healthy and safe environment for the skin of a diabetic patient, this necessitates the appropriate selection of fabrics and textile materials to be able to deal with the biological changes affecting the skin as a result of the surrounding environment. In line with the tremendous scientific development in the field of preparing fabrics and textile materials and the improvement of their functional properties to resist the growth of micro-organisms represented in bacteria and fungi and to prevent their growth and reproduction that harms the human health and the environment, it has been necessary to pay attention to the production of anti-bacterial and microbial functional clothing treated with silver.This research aimed at studying the possibility of conducting the laboratory tests on some commercially prepared silver-treated fabrics to investigate their physical properties, wear-comfort properties and resistance to bacteria.This research utilized the experimental approach in conducting the laboratory tests on some commercially prepared silver-treated fabrics including (physical and mechanical tests - testing of bacteria on two types of (S. aureus E. coli). Data was statistically analyzed by using analysis of variance and calculating averages and standard deviation.The research results revealed that the sample (S3) came as the best of the samples, which were laboratory tested. Thus, the results showed that the greater the percentage of silver fabric treatment, the greater the resistance to bacteria, and thus it can be used to improve the clothing comfort of diabetic female patients and help reduce the effects of skin diseases. The study recommends the necessity of conducting further research on fabrics treated with modern techniques to ensure their effectiveness against bacteria and to benefit from them in improving the comfort of patients' clothing in particular, and adding silver-treated fabrics partially to diabetic clothing to help reduce the effects of skin diseases.