Nature abounds in manifestations of dazzling, splendor and glory in its mountains, valleys, deserts, hills and caves, and if we contemplate nature with its creatures, we find that it conveys to the recipient a complete expression between everything that is created and the environment in which he lives or between his form and the function for which he was created, so there is no greater miracle in compatibility than Seeing fish in the water, some of which are as big as a whale or a stray of tiny worms above the surface of a stagnant lake. the research problem lies in that many of the interior designs of architecture that are inspired by nature depend on the external natural form and composition, and few of them look at creative systems that are inherently sustainable and inherent in the universe in terms of functions, principles and formal and implicit values that unify architecture and its interior design in a creative structure that gives it the characteristic of continuity., so the research aims to research on creative systems that signify sustainability from plastic and objective laws and metaphysical relationships to be a source of inspiration to reach methods, methods and solutions for sustainable creativity in the spatial structure of architecture, as well as highlighting the importance of linking the idea of inspiration with the sciences of the universe and nature to reach the formal and implicit sustainable impact on the spatial structure For architecture, and the importance of the research lies in that The research deals with the concept of creative systems that signify sustainability as a new concept that has not previously been touched upon in previous research and studies and searches for apparent and hidden creative components and systems to methods of creativity in the spatial structure of architecture as a mechanism for developing integrated sustainable design solutions that address the mind, eye and conscience,, and the research presents a set of important concepts that explain in a simple way the contents of the research, then we dealt with the idea of drawing inspiration from nature and moving to some systems indicating creativity in nature and clarifying how to be inspired by it and clarifying applied models on architecture and interior design According to each model that was presented, Results The structure of beings in nature is a system indicative of sustainability that leads to a spatial structure based on this creative systemic formation present in the components of nature, and the concept of nature no longer means those appearances and external relationships of forms only, but rather specific systems described by God Almighty for this universe, and that the matter does not It is related to our designs being inspired by nature, but rather that they improve the long-term adaptation and adaptation to life on planet Earth