The present work was carried out to control Varroa mite, Varroa destructor, in three different local districts (Bir El-Abd, El-Arish, and El Sheikh Zuwayed) in North Sinai Governorate, Egypt, during the period between 2018 and 2020. Alternative control methods, i.e. using some botanical extracts from certain wild plants i.e. Chamomile, (Matricaria chamomilla) Sage, (Salvia officinalis) and Thyme, (Thymus vulgaris). Infestations in brood and on adult honeybees as well as fallen mites were determined. Obtained results showed that, the non-treated colonies had the highest mean percentage of infested drone brood cells, worker brood cells and adult worker bees. Effect of thyme extract compared to sage, or chamomile was particularly remarkable in El-Arish district. Also, the highest number of Varroa mite fallen on the hive bottom board was recorded after the 10^th week of treatment. Thyme extract showed the highest effect on the tested mite compared to other extracts.