This study has been carried out at the Faculty of Environmental Agricultural Science, Arish University during the two successive growing seasons 2016/2017 and 2017/2018. The investigation aimed to study the effect of four organic fertilization sources on quinoa as follows (control, 4 ton fed^-1 of chicken manure (CHM), farm yard, compost, all at 10 ton fed^-1) also to assess the response of quinoa yield production and chemical composition of seed to chemical fertilization under four levels of N (control (120 kg N ha^-1), 150, 200, 250 kg N ha^-1) as urea, 46% N and their interaction. The obtained results showed that the highest values of plant height, plant weight, yield weight, 1000 seed weight and harvest index were obtained in both seasons when quinoa was fertilized with chicken manure and 250kg N ha^-1. Concerning to chemical composition of seeds, the highest values of moisture, protein, fat and ash were obtained in  both seasons when quinoa were  fertilized with chicken manure and 250kg N ha^-1 as urea, while, the highest values of carbohydrate were obtained in  both seasons when quinoa were fertilized under control treatments of both organic and N levels in both season.