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78787

UTILITY OF DIKETONE IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF NEW SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINE OF POTENTIAL BIOSIGNIFICANT INTEREST

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

General Applied Sciences

Abstract

Many heterocyclic compounds were prepared from the reaction of 2-imino-6-phenyl-2,3-dihydropyrimidin-4(5H)-one 4 with some bifunctional nucleophiles and electrophiles reagents under mild conditions .The structure of the synthesized compounds were established via their elemental and spectral analysis. Some of the products were also screened in vitro for their biological activity.

DOI

10.21608/sinjas.2017.78787

Keywords

Iminopyrimidine, pyrazolopyrimidin, dihydropyrimidin, dihydropyridine carbonitrile, pyrimidin-6-ylformimidate

Authors

First Name

Hend

Last Name

AbdElRady

MiddleName

S.

Affiliation

Dept. Chem., Fac. Sci, Arish Univ., Egypt.

Email

hendsaad02@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

AbdElReheim

MiddleName

A.M.

Affiliation

Dept. Chem., Fac. Sci, Arish Univ., Egypt.

Email

-

City

North Sinai

Orcid

-

First Name

Ibrahim

Last Name

AbdelHafiz

MiddleName

S.

Affiliation

Dept. Chem., Fac. Sci, Arish Univ., Egypt.

Email

-

City

Giza

Orcid

-

Volume

6

Article Issue

2

Related Issue

11750

Issue Date

2017-08-01

Receive Date

2020-03-24

Publish Date

2017-08-01

Page Start

213

Page End

222

Print ISSN

2314-6079

Online ISSN

2682-3527

Link

https://sinjas.journals.ekb.eg/article_78787.html

Detail API

https://sinjas.journals.ekb.eg/service?article_code=78787

Order

13

Type Code

1,210

Publication Type

Journal

Publication Title

Sinai Journal of Applied Sciences

Publication Link

https://sinjas.journals.ekb.eg/

MainTitle

UTILITY OF DIKETONE IN HETEROCYCLIC SYNTHESIS: SYNTHESIS OF NEW SUBSTITUTED PYRIMIDINES AND FUSED PYRIMIDINE OF POTENTIAL BIOSIGNIFICANT INTEREST

Details

Type

Article

Created At

22 Jan 2023