The current research aims at identifying the acquired kyphosis angle in COPD patients with reference to some physiological variables (systolic blood pressure – diastolic blood pressure – FVC – FEV1) in COPD patients and some physical variables (back muscles strength – shoulder flexibility – back bone flexibility – cardio-respiratory endurance) in COPD patients, in addition to the potentiality to predict the acquired kyphosis angle in COPD patients with reference to some physical and physiological variables under investigation. The researcher used the descriptive approach. Research community included (170) male patients of stable COPD with kyphosis angle (Cobb angle) exceeding (50̊) (age = 50.37±3.42) (height = 171.99±5.65) (weight = 80.09±5.85), from the outpatient departments and respiratory diseases of Kobry Al-Qubba and Kasr Al-Ainy Hospitals. Medical exam and diagnosis is performed by a specialized physician with fully radiology scan (front/back chest x-ray – lab tests – respiratory function tests … etc.). The researcher excluded (30) patients with cardiac failure, kidney and liver diseases, diabetes, cancer, deformities other than kyphosis. Actual sample included only (140) participants (120 as a main sample and 20 as a pilot sample). The researcher used A restameter for measuring heights and medical balance for measuring weights, X-ray device, A protractor, a ruler and a pencil for measuring Cobb angle, A manometer and a stethoscope for measuring blood pressure, A spirometer for measuring respiratory function (L), A dynamometer for measuring back muscles strength (kg), A graded ruler for measuring shoulder flexibility (cm) [finger touch behind the back] and Manual counter, a stop watch, a measuring tape and an adhesive tape for measuring cardio-respiratory endurance (the step-in-place test for 2 minutes). The researcher concluded that: Kyphosis angle for participant exceeded normal range (20-45 ̊) as its mean value was (59.59 ̊) according to Cobb angle with obvious curvature of the upper back. Blood pressure of participants was high (154.50/79.79) while FVC and FEV1 were low as FVC/FEV1 ratio was 53.5%. This indicates serious respiratory deficiency. There are no statistically significant correlations between kyphosis angle and systolic BP, diastolic BP and back bone flexibility. There is a statistically significant inverse correlation between kyphosis angle and FVC and FEV1. There is a statistically significant inverse correlation between kyphosis angle and back muscles strength, shoulder flexibility and cardio-respiratory endurance. Back muscle strength can predict kyphosis angle with a contribution percentage of (29.6%). FVC and FEV1 can predict kyphosis angle with contribution percentages of (9.7%) and (5.1%) respectively. Cardio-respiratory endurance and shoulder flexibility can predict kyphosis angle with contribution percentages of (4.5%) and (4%) respectively. Systolic BP, diastolic BP and back bone flexibility cannot predict kyphosis angle.