Fracture mechanics approaches have been employed to study the fracture behavior of the exchanger tubes made of austenitic stainless steel at elevated temperatures in fertilizer plant. Test conditions range from ambient lo elevated temperatures, monotonic to cyclic loading, and creep. Experimental work was carried on for creep, creep-fatigue interaction and fatigue at ambient and high temperatures on notched specimens. The temperature test was grouped into the range of homologous temperature (T/T)in the range of 0.177 (RT), 0.3, 0.40 and 0.50 of melting point for AISI 316 stainless steel. Furthermore experimental work has been extended by using another group of Chemical composition analysis and tensile tests were initially specimens made of AISI 304 stainless steel. performed to record the mechanical properties of both materials at room temperature Parametric representation of crack growth rate in terms of independent variables in Region II of crack growth curves has been proposed for creep, Creep-fatigue interaction and fatigue of 316 stainless steel at ambient and high temperature rates. To demonstrate the validity of the present approach, the proposed equation has been used todetermine the fatigue crack growth rate versus the change in the stress-intensity-factor relationship for AISI 304 stainless steel Based on this study, experimental results as well as analytical results obtained by using the proposed equation for AISI 316 and AISI 304 stainless steel were analyzed, and recommendations for applications are made. Thus in the present study it has been attempted to obtain a simple criterion for crack growth behavior in AISI 316 stainless steel under high temperature creep, fatigue and creep-fatigue interaction conditions.