ABSTRACT:
This work was planned to investigate the potential effect of omega
3 chitosan nanoparticles in Nile tilapia fingerlings. Two hundred forty
Nile tilapia were used into f
our groups; control diet without omega 3- chitosan nanoparticles,
omega 3- chitosan nanoparticles (0.25g/kg), omega 3- chitosan
nanoparticles (0.5g/kg) and omega 3- chitosan nanoparticles (1g/kg) for
12 weeks. Our data obtained showed that, significant differences were
found in growth parameters, including final body weight (g), body gain
(g), body gain (%), protein efficiency ratio, specific growth rate (%) and
feed conversion ratio. In addition, our data presented showed that total
cholesterol, triacylglycerdes (TAG), high-density lipoprotein (HDLc),
low-density lipoprotein(LDLc), total protein (TP), albumin, alanine
aminotransferase (ALT) and aspartate aminotransferase (AST) were
significantly affected by adding omega 3-chitosan nanoparticles in diet
and showed high significant differences (p < 0.05). However, showed no
significant differences (p > 0.05) on globulin (GLO) but were significant
differences (p < 0.05) on interleukin-1 (IL1), interleukin-6 (IL6), and fish
tumor necrosis factor (TNF-α). In molecular expression, omega-chitosan
NPs 0.5 and 1 g/kg were the most significant treated one on interleukin-1
beta (IL1- beta) but control diet in molecular expression of toll like
receptors factores 2 (TLR2) was the most significant treated one.