ABSTRACT
Rigla(Portulaca oleracea L.) is a plant used widely for its medicinal properties, many studies confirmed its role as antioxidant and antibacterial, antitumor activities, rich source of vitamins, minerals and omega-3. The aim of the present study was to investigate the effect of Riglagrinded seeds (RGS) on body weight, serum lipid profile, leptin, liver and kidney functions of female obese rats. Thirty adult female albino rats (Sprague-Dawley strain), weighing about (200±10g) were divided into two main groups, the first main group (-ve control=6 rats) was fed on basal diet. The second main group (n=24 rats) fed on high fat diet for four weak, then divided into 4 subgroups from group 2 to group 5. Group 2 (+ve control) fed on high fat diet only. Groups from 3 to 5 fed on high fat diet supplemented with 5%, 10% and 15% grinded seeds of Rigla, respectively. At the end of the experiment period (4 weeks), rats were scarified and serum was collected for biochemical analyzes. Results indicated that supplementation with Rigla caused signification decreased (p