ManageChatDiscover
210200

Evaluation of in vitro antimicrobial effects of <i>Azadirachta indica</i> (Neem) leaves extracts against selected pathogens

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Pharmaceutical microbiology

Abstract

Background:Azadirachta indica has been used against a few disease in traditional medicine and have long history of use, and their use is worldwide in both developing and devolved countries, also have multiple health benefits. This study aimed to evaluate the antibacterial activity of Neem leaves extract against standard bacterial strain and only one drug  resistant strain of important human pathogenic bacteria by using in vitro methods. Methods: This study aimed to evaluate the antimicrobial effects of Azadirachta indica (Neem) leaves extracts against selected pathogens. The present study was carried out to screen and evaluate antimicrobial activity of leaves of Azadirhta indica (Neem)methanol and petroleum ether extracts. Azadirchta indica extracts were tested against standard strains of S. aureus ATCC 6538, E. coli ATCC 25922, P. aeroginosa ATCC 9027, K. pneumonia ATCC 700603, and S. typhimurium  ATCC 14028. The effeminacy of the extracts was studied and determined by applying different concentration of extracts on the selected bacterial strains and synthetic antimicrobial discs were used as positive control by using disc diffusion method.  Results: With the statistical test analysis the comparison done showed that, no significant different between the two extracts used, and Staphylococcus aureus and Methicillin resistant staphylococcus aureus were the only bacteria susceptibly affected by this Neem extracts used. Conclusions: The result obtained indicate the leaves extracts of Neem plant have enormous antimicrobial effect, and may be exploited for the treatment of various infectious diseases

DOI

10.21608/mid.2021.109886.1213

Keywords

Azadirachta indica, Neem extracts, Staphylococcus aureus, Methicillin resistant Staphylococcus aureus

Authors

First Name

Waleed

Last Name

Fasher Bory

MiddleName

-

Affiliation

Sudan International University, Sudan.

Email

waleed77777@gmail.com

City

-

Orcid

-

First Name

Mohammed

Last Name

Hammad

MiddleName

-

Affiliation

Dar ALaloum College, Sudan

Email

medlabbsc646@gmail.com

City

-

Orcid

-

First Name

Alkhair

Last Name

Idris

MiddleName

-

Affiliation

Ahfad University for Women, Sudan.

Email

alkhair20@hotmail.com

City

Omdurman

Orcid

https://orcid.org/00

Volume

3

Article Issue

3

Related Issue

35766

Issue Date

2022-08-01

Receive Date

2021-12-06

Publish Date

2022-08-01

Page Start

744

Page End

750

Print ISSN

2682-4132

Online ISSN

2682-4140

Article File

MID_Volume 3_Issue 3_Pages 744-750.pdf

PDF . 279.1kB

Link

https://mid.journals.ekb.eg/article_210200.html

Detail API

https://mid.journals.ekb.eg/service?article_code=210200

Order

27

Type

Original Article

Type Code

1,157

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

Evaluation of in vitro antimicrobial effects of <i>Azadirachta indica</i> (Neem) leaves extracts against selected pathogens

Details

Type

Article

Created At

22 Jan 2023