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233916

Do CRP levels predict severity in COVID-19 hospitalized Egyptian patients?

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Infectious diseases
Medical virology

Abstract

Background:  Coronavirus disease 2019 (COVID-19) is a rapidly spreading virus with a wide range of clinical manifestations. To manage treatment programs and promptly assess patient severity, prognostic factors must be identified early. Objectives: The purpose of this study was to investigate if there was a link between the severity of COVID-19 and the C-reactive protein (CRP) level on admission. Methods: On admission clinical and laboratory data from 323 patients with laboratory-confirmed COVID-19 were gathered from an Isolation Hospital records from April 10, 2020 to July 30, 2020. CRP was determined in all participants using an automated analyzer and a commercially available latex-enhanced immuno-turbidimetric assay. Results: The most prevalent presenting symptom was fever (39.3%), followed by cough (38.4%).  Coronavirus disease 2019 severity and ICU admission were both predicted by high CRP levels (p < /em><0.001).  C-reactive protein levels were also greater in those who had more chest discomfort, as indicated by CT chest abnormalities (p < /em><0.001). Conclusion: Serum CRP is a simple and effective prognosticator for early prediction of COVID-19 severity.

DOI

10.21608/mid.2022.129490.1264

Keywords

COVID-19, CRP, hospital admission, ICU, severity

Authors

First Name

Mayada

Last Name

Moneer

MiddleName

-

Affiliation

Department of Internal Medicine/ Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University.

Email

mayada_moneer@med.asu.edu.eg

City

Cairo

Orcid

0000-0002-6700-9662

First Name

Shaimaa

Last Name

Fouad

MiddleName

H.

Affiliation

Department of Internal Medicine / Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University.

Email

shaimaahani@med.asu.edu.eg

City

Cairo

Orcid

0000-0003-4052-9454

First Name

Mohamed

Last Name

Allam

MiddleName

Farouk

Affiliation

Department of Family Medicine, Faculty of Medicine, Ain Shams University

Email

farouk.allam@med.asu.edu.eg

City

Cairo

Orcid

0000-0001-5954-8909

First Name

Sara

Last Name

Taha

MiddleName

I.

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Ain Shams University.

Email

dr_sara_ib@med.asu.edu.eg

City

Cairo

Orcid

0000-0001-8224-8701

First Name

Ahmed

Last Name

Okba

MiddleName

Ashraf

Affiliation

Department of Radiology, Faculty of Medicine, Ain Shams University.

Email

ahmedokba@med.asu.edu.eg

City

Cairo

Orcid

-

First Name

Amr

Last Name

Hosny

MiddleName

-

Affiliation

Department of Anesthesiology and Intensive care, Faculty of Medicine, Ain Shams University.

Email

amrhosny888@gmail.com

City

Cairo

Orcid

-

First Name

Lamiaa

Last Name

El-Moussely

MiddleName

M.

Affiliation

Department of Medical Microbiology and Immunology, Faculty of Medicine, Ain Shams University.

Email

lamia@med.asu.edu.eg

City

Cairo

Orcid

0000-0002-0385-3944

First Name

Sylvia

Last Name

Roman

MiddleName

Wefky

Affiliation

Department of Internal Medicine/ Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University.

Email

dr_sylvia2006@yahoo.com

City

Cairo

Orcid

-

Volume

3

Article Issue

3

Related Issue

35766

Issue Date

2022-08-01

Receive Date

2022-03-26

Publish Date

2022-08-01

Page Start

534

Page End

543

Print ISSN

2682-4132

Online ISSN

2682-4140

Article File

MID_Volume 3_Issue 3_Pages 534-543.pdf

PDF . 351.6kB

Link

https://mid.journals.ekb.eg/article_233916.html

Detail API

https://mid.journals.ekb.eg/service?article_code=233916

Order

5

Type

Original Article

Type Code

1,157

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023