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170477

Spread and antibiotic resistance profile of pathogens isolated from human and hospital wastewater in Ouagadougou

Article

Last updated: 25 Dec 2024

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Subjects

-

Tags

Medical bacteriology

Abstract

Background: The discharge of improperly treated hospital landfill presents an enormous public health risk. In Burkina Faso, the management of hospital's wastewaters and the current antibiotic susceptibility of clinically relevant isolates need to be determined, because the multi-drug resistant isolates have been previously described in hospital settings. The aim of this study was to determine antibiotic resistance profile of isolates circulating in Ouagadougou.
Methods: The biochemical characterization of the isolates was carried out by tests from the API 20E test and completed with molecular characterization by simple PCR. Antibiotic susceptibility of the isolates was determined using the recommendations of CA-SFM 2019.
Results: The hospital wastewaters do not undergo any treatment before been discharged into the environment. A total of 171 presumed isolates of Salmonella spp < /em>, Pseudomonas spp < /em>., and Escherichia coli were identified in this study. These isolates derived from environment (n=19) and clinical (n=152). These isolates were resistant to Amoxicillin + clavulanic acid (95.32%), Cefoxitin (72.51%), Ceftazidime (78.94%), Cefepime (80.71%), Tobramycin (59.64%), Gentamicin (42.10%), Nalidixic acid (68.42%), Norfloxacin (59.06%), Ciprofloxacin (56.14%), imipenem (0.00%), Chloramphenicol (26.31%), and Colistin (77.77%). Somewhere else, 46 presumptive Staphylococcus aureus were resistant to Vancomycin (30.43%), Oxacillin (13.04%), Penicillin G (89.13%), Ceftriaxone (15.21%), Cefoxitin (2.73%), Tobramycin (36.95%), Kanamycin (30.43%), Ciprofloxacin (15.21%), Norfloxacin (43.47%), Tetracycline (56.52%), Chloramphenicol (13.04%), and Fosfomycin (2.73%). 
Conclusion: the hospital wastewaters harbour a variety of pathogens, most of which are resistant to several families of antibiotics.

DOI

10.21608/mid.2021.72261.1143

Keywords

Multi-drug resistance, antibiotics, Effluent, hospital, Ouagadougou

Authors

First Name

Ouédraogo

Last Name

Abasse

MiddleName

Ganamé

Affiliation

Laboratory of Applied Biochemistry and Immunology, University Joseph Ki-ZERBO, Burkina Faso

Email

ganamabasse@gmail.com

City

Ouagadougou

Orcid

0000-0002-7995-790X

First Name

Kaboré

Last Name

Boukaré

MiddleName

-

Affiliation

Laboratory of Applied Biochemistry and Immunology, University Joseph Ki-ZERBO, Burkina Faso

Email

kaboreboukare27@gmail.com

City

Ouagadougou

Orcid

-

First Name

Emmanuel

Last Name

Sampo

MiddleName

-

Affiliation

CSPS of Schiphra, Burkina Faso

Email

emmanuelsampo@gmail.com

City

Ouagadougou

Orcid

-

First Name

Rober

Last Name

Bouda

MiddleName

-

Affiliation

National Office of Water and Sanitation, Burkina Faso

Email

r.bouda@netcourrier.com

City

Ouagadougou

Orcid

-

First Name

Hama

Last Name

CISSE

MiddleName

-

Affiliation

Laboratory of Applied Biochemistry and Immunology, University Joseph Ki-ZERBO, Burkina Faso

Email

cissehama70@gmail.com

City

Ouagadougou

Orcid

0000-0001-7766-9501

First Name

Kpoda

Last Name

Stéphane

MiddleName

Dissinviel

Affiliation

University of Ziniaré, Burkina Faso

Email

podadissin@yahoo.fr

City

Ouagadougou

Orcid

-

First Name

Ismail

Last Name

Odetokun

MiddleName

-

Affiliation

Department of Veterinary Public Health and Preventive Medicine, University of Ilorin, Nigeria

Email

ismail23us@gmail.com

City

Ilorin

Orcid

0000-0002-5171-1895

First Name

Adama

Last Name

Sawadogo

MiddleName

-

Affiliation

Laboratory of Applied Biochemistry and Immunology, University Joseph Ki-ZERBO, Burkina Faso

Email

damouss75@yahoo.fr

City

Ouagadougou

Orcid

0000-0003-1690-3039

First Name

Bassolé

Last Name

Henri Nestor

MiddleName

Imael

Affiliation

Laboratory of Epidemiology and Surveillance of Foodborne Diseases, University Joseph Ki-ZERBO, Burkina Faso

Email

imaelbassole160@gmail.com

City

Ouagadougou

Orcid

-

First Name

Aly

Last Name

SAVADOGO

MiddleName

-

Affiliation

Laboratory of Applied Biochemistry and Immunology, University Joseph Ki-ZERBO, Burkina Faso

Email

alysavadogo@gmail.com

City

Ouagadougou

Orcid

0000-0002-9090-290X

Volume

3

Article Issue

2

Related Issue

32908

Issue Date

2022-05-01

Receive Date

2021-04-13

Publish Date

2022-05-01

Page Start

318

Page End

331

Print ISSN

2682-4132

Online ISSN

2682-4140

Article File

MID_Volume 3_Issue 2_Pages 318-331.pdf

PDF . 805.1kB

Link

https://mid.journals.ekb.eg/article_170477.html

Detail API

https://mid.journals.ekb.eg/service?article_code=170477

Order

11

Type

Original Article

Type Code

1,157

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

Spread and antibiotic resistance profile of pathogens isolated from human and hospital wastewater in Ouagadougou

Details

Type

Article

Created At

22 Jan 2023