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110069

Seroprevalence and associated risk factors of hepatitis E virus infection among pregnant women attending Maiduguri teaching hospital, Nigeria

Article

Last updated: 25 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Medical virology

Abstract

Background: Hepatitis E Virus (HEV) is a major public health problem in developing countries and often fatal among pregnant women in the third trimester. Objectives: The study investigated the sero-prevalence and risk factors of HEV infection among pregnant women attendee of University of Maiduguri Teaching Hospital, Maiduguri, Nigeria. Methods: The cross-sectional study was carried out between 4th January 2016 to 30th May, 2016. One hundred and eighty blood samples from pregnant women who consented and enrolled for the study were analyzed for anti – HEV IgM using a quality assured commercial Enzyme Linked Immunosorbent Assay (ELISA) kit. Structured questionnaires were used to collate the sociodemographic characteristics and risk factor of study subjects. Results: Out of the 180 pregnant women sampled, the anti-HEV IgM seroprevalence of 13.3% was recorded.  The seroprevalence was significantly higher in the age range of 31 – 35 years (26.5%) and least in age range ≤ 20 years (4.9%) (p=0.009).  The highest seroprevalence was recorded in the third trimester 14.1% followed by second (p>0.05). After logistic regression, nature of toilet system, and source of water consumption were significant risk factors for active HEV infection (p˂0.05). Conclusion: Based on the 10.8 % pooled national prevalence of HEV infection in Nigeria, this study recorded a significantly high level of anti – HEV IgM seropositivity, an indication of recent and active HEV infection among pregnant women at the study area. Also, these infections are most among the pregnant women in their third trimester. HEV infection was related to personal, water and environmental hygiene.

DOI

10.21608/mid.2020.39788.1053

Keywords

HEV Infection, risk factor, Faeco-Oral transmission, seroprevalence, Nigeria

Authors

First Name

Babajide

Last Name

Ajayi

MiddleName

Bamidele

Affiliation

Department of Microbiology, School of Sciences, Federal University of Technology Akure, Nigeria

Email

ajayi@yahoo.com

City

-

Orcid

-

First Name

Iman

Last Name

Igwegbe

MiddleName

-

Affiliation

Department of Medical Laboratory Science, College of Medical Sciences, University of Maiduguri, Nigeria

Email

eemn1@yhoo.com

City

-

Orcid

-

First Name

Semsari

Last Name

Latbone

MiddleName

-

Affiliation

Department of Medical Laboratory Science, College of Medical Sciences, University of Maiduguri, Nigeria

Email

latbone@yahoo.com

City

-

Orcid

-

First Name

Bamidele

Last Name

Oderinde

MiddleName

Soji

Affiliation

Department of Medical Laboratory Science, College of Medical Sciences, University of Maiduguri, Nigeria

Email

sojihunta@yahoo.com

City

-

Orcid

-

First Name

Ibrahim

Last Name

Kida

MiddleName

Musa

Affiliation

Department of Medicine, University of Maiduguri Teaching Hospital, Maiduguri Nigeria

Email

kidaib@yahoo.com

City

-

Orcid

-

First Name

Samuel

Last Name

Oyinloye

MiddleName

Oyebode

Affiliation

Department of Microbiology, Faculty of Science, University of Maiduguri, Borno State, Nigeria

Email

oyesam@yahoo.com

City

-

Orcid

-

First Name

Kayode

Last Name

Adelowo

MiddleName

-

Affiliation

Department of Immunology, University of Maiduguri Teaching Hospital, Maiduguri Nigeria

Email

kaykayol@gmail.com

City

-

Orcid

-

First Name

Ballah

Last Name

Denue

MiddleName

Akawu

Affiliation

Department of Medicine, University of Maiduguri Teaching Hospital, Maiduguri Nigeria

Email

denueb@yahoo.com

City

-

Orcid

-

First Name

Calvin

Last Name

Chama

MiddleName

-

Affiliation

Department of Obstetrics and Gynaecology, University of Maiduguri Teaching Hospital, Maiduguri Nigeria

Email

calvincc@gmail.com

City

-

Orcid

-

First Name

Idris

Last Name

Abdullahi

MiddleName

Nasir

Affiliation

Department of Medical Laboratory Science, Faculty of Allied Health Sciences, Ahmadu Bello University Zaria Nigeria

Email

eedris888@yahoo.com

City

-

Orcid

0000-0002-5511-1272

Volume

3

Article Issue

1

Related Issue

29888

Issue Date

2022-02-01

Receive Date

2020-07-19

Publish Date

2022-02-01

Page Start

62

Page End

68

Print ISSN

2682-4132

Online ISSN

2682-4140

Article File

MID_Volume 3_Issue 1_Pages 62-68.pdf

PDF . 333.5kB

Link

https://mid.journals.ekb.eg/article_110069.html

Detail API

https://mid.journals.ekb.eg/service?article_code=110069

Order

8

Type

Original Article

Type Code

1,157

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

Seroprevalence and associated risk factors of hepatitis E virus infection among pregnant women attending Maiduguri teaching hospital, Nigeria

Details

Type

Article

Created At

22 Jan 2023