169076

Cutaneous infections among Human Immunodeficiency Virus (HIV) - infected patients in a single center in Kuala Lumpur, Malaysia

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Infectious diseases
Medical virology

Abstract

Background: Human immunodeficiency virus (HIV) infection is frequently associated with cutaneous infections. Objective: To determine the spectrum of dermatological infections among HIV positive patients, identify the causative microorganisms and CD4 count. Methods: This is a retrospective study conducted in a tertiary center. HIV-positive patients registered in 2013 to 2018 were identified from casemix database, those with suspected cutaneous infection were selected. Data was obtained from electronic and physical medical records. Results:  A total of 27 patients were enrolled. Mean age was 38.61±11 years, 22(81.5%) were males and 5(18.5%) were females. Most patients 14(52%) developed more than one skin disease, there were a total of 46 diagnoses. The skin infections were fungal 11(24%), viral 4(8.7%) and bacterial 4(8.7%). Disseminated mycoses were mostly due to Penicillium marneffei 4(8.7%). Superficial fungal infections were due to Fusarium sp, Candida sp and Trichosporum sp < /em>. Cutaneus candidiasis constituted 3(6.47%). The average CD4 count in patients with fungal infections was 79 cells/mm3. Other skin diseases documented were adverse cutaneous drug reactions 8(17.4%) and pruritic papular eruption 5(11%). CD4 count was Conclusion: Both disseminated and superficial fungal infections were common in our cohort. Penicillium marneffei caused majority of disseminated infections while superficial infections are due to moulds.

DOI

10.21608/mid.2021.71180.1140

Keywords

human immunodeficiency virus, acquired immunodeficiency syndrome, skin, Infection

Authors

First Name

Ahlam

Last Name

Muthanna

MiddleName

Mutahar

Affiliation

Dermatology, Faculty of Medicine, The National University of Malaysia, Kuala Lumpur, Malaysia

Email

ahlammutahar@hotmail.com

City

Kuala Lumpur

Orcid

0000-0002-7429-1176

First Name

Adawiyah

Last Name

Jamil

MiddleName

-

Affiliation

Professor, Dermatology Department, Faculty of Medicine, The National University of Malayisa, Kuala Lumpur, Malaysia

Email

adda_jamil@yahoo.com

City

-

Orcid

-

Volume

3

Article Issue

1

Related Issue

29888

Issue Date

2022-02-01

Receive Date

2021-04-05

Publish Date

2022-02-01

Page Start

55

Page End

61

Print ISSN

2682-4132

Online ISSN

2682-4140

Link

https://mid.journals.ekb.eg/article_169076.html

Detail API

https://mid.journals.ekb.eg/service?article_code=169076

Order

7

Type

Original Article

Type Code

1,157

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

Cutaneous infections among Human Immunodeficiency Virus (HIV) - infected patients in a single center in Kuala Lumpur, Malaysia

Details

Type

Article

Created At

22 Jan 2023