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Prevalence of hepatitis B virus coinfection among Human Immunodeficiency Virus positive patients in Yola, Adamawa State, Nigeria

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Medical virology

Abstract

Background: Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) confection has been reported to impair negatively on the health of the patients because it impacts directly on the outcome of HBV infection, considerably complicating its natural history, diagnosis and management. This study was aimed at determining the incidence and distribution of HBV/HIV coinfection in the study area. Methods: The sera people living with HIV/AIDS were screened for hepatitis B surface antigen (HBsAg) and cluster of differentiation 4 (CD4) cell counts using the Becton Dickinson Fluorescence Activated Cell Sorter procedure. Results: The prevalence of HBV co-infection among people living with HIV/AIDS in this study was 11% with the coinfection being higher in males (14.3%) compared to the 9.7% among females. The coinfection was highest among people ages 25-39 yr. (12.9%) while least occurrence of coinfection was observed in ages above 53 yr. (8.3%). The CD4 counts of HBV and HIV coinfected persons showed that 18.2% of coinfected persons had CD4 counts above 700-1000 cells/mm3 while 12.1% had CD4 counts between 501-700 cells/mm3. Conclusion: The relatively high prevalence of HBV infection in HIV patients confirms the need for baseline screening for these markers in HIV-infected patients, as this could affect the choice of highly active antiretroviral therapy (HAART) regimen for the patients.

DOI

10.21608/mid.2021.64091.1126

Keywords

Coinfection, HBV, HIV, Distribution

Authors

First Name

MUSA

Last Name

SALE

MiddleName

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Affiliation

Department of Microbiology, Modibbo Adama University of Technology, Yola, Nigeria

Email

samupuk@mautech.edu.ng

City

-

Orcid

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First Name

Amira

Last Name

Bagarmi

MiddleName

-

Affiliation

Department of Microbiology, School of life Sciences Modibbo Adama University of Technology, Yola, Nigeria

Email

amirabagarmi@yahoo.com

City

-

Orcid

-

First Name

Shinjawa

Last Name

Yunana

MiddleName

-

Affiliation

Pathology Department, Adamawa State Specialist Hospital Yola, Nigeria

Email

shinjawayunana@yahoo.com

City

-

Orcid

-

Volume

3

Article Issue

1

Related Issue

29888

Issue Date

2022-02-01

Receive Date

2021-01-20

Publish Date

2022-02-01

Page Start

48

Page End

54

Print ISSN

2682-4132

Online ISSN

2682-4140

Link

https://mid.journals.ekb.eg/article_158071.html

Detail API

https://mid.journals.ekb.eg/service?article_code=158071

Order

6

Type

Original Article

Type Code

1,157

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023