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108044

Hepatitis B vaccination coverage rate and immune response among primary health care workers in Sarajevo Canton, Bosnia and Herzegovina

Article

Last updated: 22 Jan 2023

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Subjects

-

Tags

Medical virology

Abstract

Background: Immunization is a key step in preventing the occupational risk of acquiring hepatitis B infection for healthcare workers (HCWs).
Objective: The aim of the study was determination the hepatitis B vaccine (HepB) coverage rate among HCWs and support staff and immune response 10 years after primary vaccination.
Methods: A retrospective study was conducted in the Public Institution Health Centre of Sarajevo Canton in Bosnia and Herzegovina. Second-generation vaccines Euvax (Sanofi Pasteur, Thailand/LG Life Sciences Ltd, Korea) and Engerix B (GlaxoSmithKline, Belgium) were applied. A level of ≥ 10 IU/L anti-HBs was set as a cut-off value indicating the presence of protective immunity against new HBV infections and successful vaccination.
Results: In total, 1541 (75.80%) were fully vaccinated, out of 1126 (73.07%) were females. The median age of participans was 50.5 ± 9.4 years. Control measurement of the anti-HBs level was performed for 409 (26.54%) HCWs. During the research, 37 booster doses were administered. Of the 23 retested participants, anti-HBs ≥10 IU/L were observed in 19 (82.16%). Three non-reactors subject were revealed.
Conclusions: A satisfying HepB coverage rate and a high protective rate against hepatitis B infection among HCWs and support staff was achived. These results indicate the active engagement of the institution in the implementation of preventive measures and the high level of awareness regarding the significance of immunization. Our results demonstrated the effectiveness of booster doses. A low prevalence of non-reactors was revealed. Additional research with a focus on occupational risk factors in dental service is advised.

DOI

10.21608/mid.2020.36483.1038

Keywords

Hepatitis B virus, Hepatitis B vaccine, Immune Response, Health Care Workers, Bosnia and Herzegovina

Authors

First Name

Sabina

Last Name

Šegalo

MiddleName

-

Affiliation

Department of Medical Microbiology, Parasitology and Virology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Email

sabina.segalo11@gmail.com

City

Sarajevo

Orcid

0000-0002-9280-3278

First Name

Emina

Last Name

Kiseljaković

MiddleName

-

Affiliation

Department of Medical Biochemistry, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Email

emina.cengic@gmail.com

City

-

Orcid

-

First Name

Lejla

Last Name

Berhamović

MiddleName

-

Affiliation

Department for Prosthodontics and Dental Implantology, Faculty of Dentistry with Clinics, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Email

lejlaberhamovic1974@gmail.com

City

-

Orcid

-

First Name

Arzija

Last Name

Pašalić

MiddleName

-

Affiliation

Department of Sanitary Engineering, Faculty of Health Studies, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Email

arzijapasalicarz@gmail.com

City

-

Orcid

-

First Name

Sabina

Last Name

Mahmutović Vranić

MiddleName

-

Affiliation

Department of Medical Microbiology, Parasitology and Virology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Email

sabinamahmutovicvranic@gmail.com

City

-

Orcid

-

First Name

Emir

Last Name

Berhamović

MiddleName

-

Affiliation

Department for Prosthodontics and Dental Implantology, Faculty of Dentistry with Clinics, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Email

emirberhamovic1969@gmail.com

City

-

Orcid

-

First Name

Daniel

Last Name

Maestro

MiddleName

-

Affiliation

Institute for Public Health Federation Bosnia and Herzegovina Department of Sanitary Engineering, Faculty of Health Studies, University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Email

danielmaestrobih@gmail.com

City

-

Orcid

-

First Name

Anes

Last Name

Jogunčić

MiddleName

-

Affiliation

Department of Physiology, Medical School, Sarajevo School of Science and Technology, Sarajevo, Bosnia and Herzegovina

Email

anesjoguncic2020@outlook.com

City

-

Orcid

-

First Name

Aleksandra

Last Name

Pašić

MiddleName

-

Affiliation

Department of Clinical Chemistry and Biochemistry, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina

Email

pasicsandra1971@gail.com

City

-

Orcid

-

Volume

2

Article Issue

1

Related Issue

19260

Issue Date

2021-02-01

Receive Date

2020-07-20

Publish Date

2021-02-01

Page Start

60

Page End

67

Print ISSN

2682-4132

Online ISSN

2682-4140

Article File

MID_Volume 2_Issue 1_Pages 60-67.pdf

PDF . 745.0kB

Link

https://mid.journals.ekb.eg/article_108044.html

Detail API

https://mid.journals.ekb.eg/service?article_code=108044

Order

11

Type

Original Article

Type Code

1,157

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023