The research aims to identify the effect of using ozone gas on some functional indicators and the delay of onset of fatigue for wrestlers. The researcher used the experimental method using two experimental and one other officer of the appropriateness of the nature of the search Research sample. The sample was selected intentionally from wrestlers with a 16 years old average of age and were divided into an experimental group of (5) wrestlers and a control group also of (5) wrestlers. As shown in Table (1, 2) of the statistical demographics and the parity of the data of the sample's (basic and physiological) variables. Attachment (1) Conclusions: The pulse rate of the wrestlers decreased from (210.80) b/sec. to (183.80) b/sec. after the experiment. Red blood cells in the blood of the wrestlers increased from (4.49) Thousnd/ul to (5.38) Thousnd/ul after the experiment. The percentage of hemoglobin in the blood of the wrestlers increased from (12.98) g/dl to (14.72) g/dl after the experiment. The percentage of hematocrit in the blood of the wrestlers increased from (38.42%) to (45.72%) after the experiment. The percentage of lactic acid in the blood of the wrestlers decreased from (74.98) Mmole/l to (26.97) Mmole/l after the experiment