The current research aims to identify the relations between ACE polymorphism and improvements of some physical variables in boxers. The researchers used the experimental approach (one-group design) with pre- and post-measurements. Research community included (13) young boxers (17-19 years) from ALSEKKA ALHADID Sports Club, Tanta Sorts Club and GHAZL Tanta Sports Club who are registered at the Egyptian Federation of Amateur Boxing. The researchers purposefully chose (8) boxers as a main sample while the other (5) were chosen for pilot sample.  Participants were categorized according to their genetic type into two groups: group one (ACE DD) included (5) boxers – group two (ACE ID) included (3) boxers. Results indicated that: Boxers of ACE DD group are characterized by speed endurance and speed strength compared with ACE ID group. Differences in relative variance were 66.64% and 20.8% and 24.38% on speed endurance and speed strength (right/lift) respectively in favor of ACE DD group. Boxers of ACE ID group are characterized by strength endurance compared to ACE DD group as difference in relative variance was 47.34% in favor of ACE ID group. There were no statistically significant differences between ACE DD and ACE ID groups on coordination as difference in relative variance was only 2.24% in favor of ACE DD group.