The current research aims to design some respiratory and rehabilitative exercises for hospitalized post-operative recovery of open-heart surgery male patients in addition to identifying its effects on cardio-vascular functioning (pulse – blood pressure – vital capacity – 1-min breathing rate – blood oxygen levels). The researcher applied the experimental approach (two-group design) with pre- and post-measurements. Research community included all open-heart surgery male patients (40-50 years) from Magdi Yacoub' Institute for heart diseases and research. Sample (n=16) was purposefully chosen after approval of the responsible physician and written consents of patients. Participants were divided into two groups (experimental = control = 8). The respiratory exercises were applied (3) time a day. Total number of sessions was (12) with session duration of (15-35) minutes. The researcher concluded that: