Purpose: to evaluate the effects of Manual Therapy in Hypertensive Patients.

Methods: Sixty patients with primary hypertension were participated in this randomized clinical trial. The patients were randomly divided into two groups (control and an intervention group). We applied Manual Massage Therapy to the study group beside the medical treatment prescribed by the physician, but the control group takes only the medical treatment. In both groups, blood pressure was measured and recorded before and after the Manual Therapies Massage applications for 3 months. The study data were collected by using carefully a questionnaire including demographic information, a check list of blood pressure record, and also a fixed manometer.

Results: In the intervention group, systolic and diastolic blood pressure decreased remarkably in the Study group more than in the control group, respectively after Manual therapy massage (P<0.001).

Conclusion: The obtained results were indicative of the effectiveness of manual therapy in reducing blood pressure in the study participants. Using stress control interventions, such as manual massage, is a simple, acceptable, and teachable method for families to control blood pressure. After conducting more studies on this issue, manual therapy can be recommended as a non-pharmacological method to control blood pressure.