In Egypt and many countries, Construction sites are among the hazardous places where injuries and fatalities workplace of workers commonly happen. The average number of accidents was 16.03, and the proportion of accident occurrences concerning the total number of people was 62.8 percent. Due to the high number of accidents that occur in construction and the consequences, this has for workers, organizations, society, and countries, occupational safety, and health (OSH) has become a critical issue for stakeholders to take care of the human resource. For this reason, the classification of documents was carried out following the Occupational Safety and Health Cycle, composed of five steps: regulation, education and training, risk assessment, risk prevention, and accident analysis. We then used the knowledge acquired, objective results, and lessons learned to develop recommendations related to the profile, main functions, and best practices for health and safety coordination performance. Most accidents could have been prevented if the OSH principles had been put into practice at workplaces in Egypt.