This study investigated the levels of selected heavy metals and their potential health risks to consumers within Lokoja metropolis, Kogi State, Nigeria. Fresh pumpkin (Telfairia occidentalis) leaves, obtained from major (International, Old Market, Kpata and Lokongoma) markets within Lokoja, were analyzed for copper (Cu), zinc (Zn), lead (Pb), cadmium (Cd), Nickel (Ni) and manganese (Mn) using standard atomic adsorption spectrophotometer. Daily intake of metals (DIM), target hazard quotient (THQ)/hazard index (HI) and target cancer risk (TCR), were then determined to assess the potential health risks of the metals. Concentrations of Cd (0.18 ± 0.02 and 0.16 ± 0.02 mg/kg), Pb (0.08 ± 0.11 mg/kg and 0.05 ± 0.10 mg/kg) and Zn (1.82 ± 0.04 mg/kg and1.76 ± 0.01 mg/kg) were significantly highest (p < 0.05) in vegetable samples from International and Old Markets when compared with Lokonguma and Kpata Markets which were not significantly different (p˃0.05) from each other. There were insignificant non-carcinogenic risks for the metals except for Cd which could pose risks when the daily ingestion rate is tripled. Target cancer risks were in the increasing order PbT. occidentalis poses subantantilly low health risks when consumed moderately except for Cd, Ni and Cu when the daily consumption rate is significantly increased over a life time period. Hence, intensive awareness campaigns are recommended to enlighten farmers/retailers on safer ways of cultivation/handling of green leafy vegetables.