This study aimed to evaluate the effect of Jojoba Oil and nanoparticles of Silver supplementation on growth performance, viability and economics in broiler chickens. A total of 192 Ross 308 broiler chicks (1-day-old) were allocated to 4 experimental treatments: CONT (control diet), JO (CONT diet with 150 mg/kg of Jojoba oil), Nano-Ag (CONT diet with 4 mg/kg nanoparticles of Silver), and JO+Nano-Ag (CONT diet plus Jojoba Oil and nanoparticles of Silver). Each treatment had 6 replicates of 8 birds. The experiments lasted for 35 days. Starter and grower diets, based on corn and soybean meal, and water were available ad libitum. Body weight and feed intake were measured from 0 to 35 days. Body weight gain and feed conversion ratio were calculated. Survivability rate and cost economics were calculated. Statistical comparisons were performed using a One-way ANOVA. Supplementation of JO and Nano-Ag separately as well as in the form of combined usage, increased (P<0.05) body weight and body weight gain compared to CONT. Supplementation of broiler diets with JO, Nano-Ag or their combination improved feed conversion ratio, without any significant effect on feed intake. Interestingly, a lower mortality rate was recorded in the supplementation groups and, therefore, a higher net return was observed. Hence, the present study demonstrates that supplementation of JO and Nano-Ag separately as well as in the form of combined usage, improved growth performance and economic return of broiler chickens.