The present work relates to estimate the effect of magnetically-treated saline water on physiological and agronomic traits of 22 bread wheat genotypes and to determine the changes in soil properties. Replicated pot experiments involving potable water, saline water (2500 and 5000 ppm) and magnetically treated (2500 and 5000 ppm saline water) were conducted in greenhouse during 2017/2018 and 2018/2019 winter seasons at Faculty of Agriculture, Sohag University, Sohag, Egypt. The results showed the magnetically treated 2500 and 5000 ppm saline water had positive effects on chlorophyll concentration by 7.29% and 7.96% and canopy temperature by -6.14 % and -3.93% when compared with 2500 and 5000 ppm saline water, respectively. Moreover, the percent of increase due to using 2500 and 5000 ppm saline water treated with magnetic reached to 4.25 and 8.42% for plant height, 3.7 and 13.43% for number of spikes/plant, 1.43 and 4.09% for spike length, 15.42 and 16.55% for 100 kernel weight, 6.52 and 6.15% for biological yield/plant and 9.94 and 5.41% for grain yield/plant compared to irrigation with 2500 and 5000 ppm saline water, respectively. Also, the mean values of soil soluble cations and anions were less in soil irrigated with treated magnetic water than that irrigated with untreated magnetic water (having salinity of 2500 and 5000 ppm). It could be that the treated magnetic water could effectively increase the physiological and agronomic traits. But indeed, more studies are needed to declare the influence of magnetic water on the growth, yield and quality of other different crops.