Nowadays, nanotechnology is more frequently used with the presence of new tools for utilizing nanoparticle-sized essential elements, enhancing the animal's ability to absorb these elements and thereby improving their productive and reproductive performance. Zinc oxide nanoparticles (Nano-ZnO) can promote productive performance, act as antibacterial agents, and influence the immunity and reproduction of the rabbits. Moreover, zinc (Zn) increases semen volume, total live sperm concentration, percentage of sperm motility, and conception rate in heat-stressed rabbits. Several studies have already reported the effects of low and high zinc doses on rabbit performance. The most observed and analyzed reproductive performance variables are semen quality, spermatogonia, and meiosis of spermatocytes. Most of the studies showed slight positive effects; however, significant results were rare. Since there are almost unlimited possibilities regarding the zinc dosage, further research is still required. Nano-sized zinc particles can be used at low doses, resulting in better outcomes than conventional zinc sources. This review provides an overview of and illustrates the positive effects of zinc nanoparticles and their potential application as a mineral supplement to rabbit diets.