Orthohantavirus is a genus of single-stranded, enveloped, negative-sense RNA viruses in the
family Hantaviridae within the order Bunyavirales. Members are called orthohantaviruses or
simply hantaviruses. Hantavirus pulmonary syndrome (HPS), Hantavirus is a life-threatening
zoonotic disease characterized by pulmonary edema, hypoxia, and hypotension, started by vague
flu-like symptoms or can involve hemorrhagic fever and renal syndrome (HFRS). Hantaviruses
are transmitted by contact with the bodily fluids of rodents, particularly from saliva from bites
and especially from inhalation of viral particles from urine and feces in aerosols. Among the
HCPS-causing hantaviruses is the Andes orthohantavirus, the only hantavirus confirmed to be
capable of spreading from person to person, though this is rare!!! Generally speaking, the virus
diseases are a continued threat to human health in both community and healthcare settings
worldwide.