Breast-conserving surgery (BCS) is considered the gold-standard treatment for early breast cancer.
Various techniques were proposed for identifying non-palpable breast tumors, but the most
popular one is the wire-guided localization (WGL technique). The most important drawback of
BCS is the possible presence of microscopic tumor at or close to the margin of excision.
The work highlighted significance of screening programs in early detection and recent advances
in the management of early non palpable breast cancer. This was a prospective study on 30 patients
with a single non-palpable breast lesion. A preoperative USG or MMG-guided hook wire
localization technique was performed then intraoperative frozen section was done.
The results showed that 30 patients were treated with wire-guided localization and BCS, andintraoperative
frozen sections. According to positive margins, patient age, menopausal status, tumor
size and histologic type were associated with increased risk of positive margins. The re-excision
at the time of original operation was 6/30(20%), without second operation. Postoperative complications
were 5(16.7%) due to neo-adjuvant chemotherapy, size of mass, specimen volume, margin
status and LNs affection.