HIV/ADIS is one of uprising problem in Egypt as UNAIDS Estimated that more than 22 thousand people infected at the end of 2018 this represent less than 1% of population. Without screening in high risk groups and prompt management of infected patients this may lead to spreading of infection and death from opportunistic infections. The present study identified clinical presentations, characteristics of patients and risk factors associated with infection in positive HIV patients attended to Abassia Fever Hospital in a year (2015-2016). Data of clinical presentations and demographic characteristics of 100 consecutive patients were collected during admission. The results showed that 82% of patients were from urban area and 18% from rural area and 93% of patients were smoker (65%), married (80%) and were on regular
HAART. Regarding clinical manifestations and CD4 count; 68% of the patients had ADIS criteria, 30% had diarrhea, 28% had chest infections, 59% had anemia and 64% had CD4 count less than 200cells/ μL however a single case had presented with Kaposi sarcoma.