Spontaneous Bacterial Peritonitis (SBP) is a frequent and severe complication in patient with cirrhosis and ascites due to CLD with high mortality rate (20%-40%). SBP causes an inflammatory reaction resulting in an increased number of PMNs in ascitic fluid. It was reported that diagnosis of SBP is established when the ascitic fluid PMN count is greater than 250 cells/mm3 Lysis of the PMNs during transport to the laboratory, may occur which may lead to false negative
results. This study evaluated the usefulness of some recent parameters for diagnosis of SBP that can be used for future development of a rapid bedside test. Identifying a sensitive marker that can be used for rapid diagnosis of SBP in cirrhotic patients will have important clinical and economic consequences for this group of patients and also for clinicians involved in their cares. This study was conducted on 100 patients with ascites admitted to Tropical Medicine department,
Al-Azhar University Hospitals in the period from January 2015 to August 2015. The results showed that there was a highly significant positive correlation between ascetic fluid LAF level and neutrophils in ascitic fluid in cases of SBP, Also there was positive correlation between ascetic fluid LAF and ascetic fluid LDH (p value<0.001).