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77962

REVIEW ON BONE DISEASE (OSTEOPOROSIS) IN DIABETES MELLITUS

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Last updated: 25 Dec 2024

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Abstract

Osteoporosis is the most common bone disease known, affecting an estimated 200 million people worldwide. Approximately 30% of all postmenopausal women are affected and up to 40% developed a fragility fracture within their lifetime. Over time, a number of risk factors have been associated with osteoporosis and are useful when used in screening tools and treatment algorithms. Diabetes, although identified more than half a century ago as being associated with bone frailty, has come to the forefront only within last decade as an important osteoporosis risk factor. While both type 1 (DM1) and type 2 (DM2) diabetes increased fracture risk, the link is far more profound with DM1. DM1 accounts for approximately 5% of all cases of diabetes in the USA and is associated with a 6.4–6.9-fold increase in the relative risk of hip fracture compared to individuals without diabetes. As life expectancy continues to increase for those living with DM1, an increase in number of fractures occurring in this population is expected in the future. For understanding of bone fragility in DM1 calls for an update of diabetes guidelines, better screening tools, and more research into the use of therapeutic strategies in these patients.

DOI

10.21608/jesp.2017.77962

Keywords

Osteoporosis, Diabetes mellitus, type 1 and type 2, Man, Woman

Authors

First Name

AHMED

Last Name

EL-TAWDY

MiddleName

HASSAN FAWZI

Affiliation

Military Medical Academy, Cairo 11291, Egypt.

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Orcid

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First Name

EISSA

Last Name

IBRAHIM

MiddleName

ABDEL HAMED

Affiliation

Military Medical Academy, Cairo 11291, Egypt.

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City

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Orcid

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First Name

EMAN

Last Name

AL SAKHAWY

MiddleName

MAHMOUD ALY

Affiliation

Military Medical Academy, Cairo 11291, Egypt.

Email

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City

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Orcid

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First Name

TOSSON

Last Name

MORSY

MiddleName

A.

Affiliation

Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt.

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City

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Orcid

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Volume

47

Article Issue

1

Related Issue

11647

Issue Date

2017-04-01

Receive Date

2020-03-18

Publish Date

2017-04-01

Page Start

35

Page End

46

Print ISSN

1110-0583

Online ISSN

2090-2549

Link

https://jesp.journals.ekb.eg/article_77962.html

Detail API

https://jesp.journals.ekb.eg/service?article_code=77962

Order

5

Type

Original Article

Type Code

1,127

Publication Type

Journal

Publication Title

Journal of the Egyptian Society of Parasitology

Publication Link

https://jesp.journals.ekb.eg/

MainTitle

REVIEW ON BONE DISEASE (OSTEOPOROSIS) IN DIABETES MELLITUS

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Article

Created At

22 Jan 2023