The paradigm shift of undergraduate medical education in Egypt to competency based and the change role of basic medical sciences from knowledge acquisition in disciplines to contextual learning related to future graduate career. The present work represents a prototype how parasitology and other basic sciences are incorporated with paediatrics as early as the second year of study, although an in-depth paediatrics courses will be in the clerkship phase. A holistic approach for the clinical presentation “Watery diarrhoea in 6 years old immunocompromised child under chemotherapy in a hospital ward" is represented in relation to different relevant learning theories in team based and task based learning strategies for promoting authentic learning since early in undergraduate medical curriculum.