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68190

ANTI-NUCLEAR ANTIBODY (ANA) PATTERNS IN EGYPTIAN SYSTEMIC LUPUS ERYTHEMATOSUS

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Last updated: 04 Jan 2025

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Abstract

In fact autoantibodies are immunoglobulins against self-antigens that are known as endogen antigens. Systemic lupus erythematosus (SLE) is an occasion that the body begins a fight against its own cells and organs. There are different types of autoantibodies that have been identified in recent years. The most familiar is anti-nuclear antibodies (ANA). They are created against cell nuclei, and one of the methods used for its detection and its pattern determination is indirect immunofluorescence test (IIF). IIF was used for that purpose in our study, and concluded that ANA positivity rate was higher in female patients than the male ones, where ANA was positive in 36.1% of the male patients and 48.2% of female patients. Also, the most frequent ANA patterns in SLE patients were speckled pattern, where 21.6% & 41.3% of male
and female patients, respectively, have speckled pattern of ANA.

DOI

10.21608/jesp.2019.68190

Keywords

Egypt, Systemic lupus erythematosus, Anti-nuclear antibody

Authors

First Name

AZZA

Last Name

ELAMIR

MiddleName

M.

Affiliation

Department of Zoology, Faculty of Science, Cairo University, Giza, Egypt.

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First Name

ALYAA

Last Name

FARID

MiddleName

A.

Affiliation

Department of Zoology, Faculty of Science, Cairo University, Giza, Egypt.

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City

-

Orcid

-

First Name

ESRAA

Last Name

AMIN

MiddleName

S.

Affiliation

Faculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6th October City, Giza, Egypt.

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-

Orcid

-

First Name

HEBA

Last Name

HASSAN

MiddleName

A.

Affiliation

Faculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6th October City, Giza, Egypt.

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-

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-

Orcid

-

First Name

MOHAMED

Last Name

MAGED

MiddleName

M.

Affiliation

Faculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6th October City, Giza, Egypt.

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-

City

-

Orcid

-

First Name

AHMED

Last Name

AREF

MiddleName

A.

Affiliation

Faculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6th October City, Giza, Egypt.

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Volume

49

Article Issue

2

Related Issue

10317

Issue Date

2019-08-01

Receive Date

2020-01-14

Publish Date

2019-08-01

Page Start

451

Page End

454

Print ISSN

1110-0583

Online ISSN

2090-2549

Article File

JESP_Volume 49_Issue 2_Pages 451-454.pdf

PDF . 225.8kB

Link

https://jesp.journals.ekb.eg/article_68190.html

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https://jesp.journals.ekb.eg/service?article_code=68190

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Original Article

Type Code

1,127

Publication Type

Journal

Publication Title

Journal of the Egyptian Society of Parasitology

Publication Link

https://jesp.journals.ekb.eg/

MainTitle

ANTI-NUCLEAR ANTIBODY (ANA) PATTERNS IN EGYPTIAN SYSTEMIC LUPUS ERYTHEMATOSUS

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Article

Created At

22 Jan 2023