Introduction: The purpose of this study was to investigate the effectiveness of debonding ceramic brackets using an Er,CR:YSGG laser. Materials and methods: Sixty Clarity (3M) ceramic brackets were bonded to human premolar teeth which were randomly divided into three equal groups. The first group was debonded without performing previous laser application. The Er,Cr:YSGG laser was used for group 2 at 2.5W and for group 3 at 3.5W. The laser was applied at two points on each bracket for 20 seconds each. Shear bond strengths were measured in megapascals with a universal testing machine and adhesive remnant index scores were recorded. Results: Statistically significant lower shear bond strengths were found in the lased groups compared with non-lased group. The adhesive remnant index scores were statistically significant; the lased groups had scores of 2 or 3. Conclusion: The Er,Cr:YSGG laser was effective for debonding ceramic brackets and significantly decreased debonding force, thus decreased the risk of enamel damage.