Introduction: Recently, air-abrasion technology has been examined for potential applications within the field of orthodontics as an alternate method of enamel surface treatment especially with the introduction of intraoral sand blasters. Therefore, the aim of this study was to compare the effect of sandblasting of enamel before and after conventional acid-etch bond technique on the shear bond strength. Methods: the study consisted of sixty freshly extracted human premolars that were equally and randomly divided into two groups (A and B). In group A the enamel surface treatment involved sandblasting followed by acid etching, while in group B enamel surface treatment involved acid etching followed by sandblasting. Shear bond strength was tested by Instron universal testing machine in shear mode until bond failure and recorded in Newtons then converted into MPa. The mean results for shear bond strengths in group A were 12.31 MPa while those for group B were 10.35 MPa and the P-value was 0.02*. Conclusion sandblasting followed by acid etching resulted in the highest shear bond strength; while acid etching followed by sandblasting resulted in statistically significant lower shear bond strength although it is still clinically acceptable.