Background: Maxillary canines are important aesthetically and functionally, but impacted canines are more difficult and time consuming to treat. Moreover, impacted canines vary greatly in the inclination and location and can lead to resorption of neighboring incisors. Aim: To locate the impacted canine and compare resorption cases with non-resorption cases. Methods: Thirty -five 3 D CBCT scans were evaluated 17 presented with bilateral palatal impactions and 18 with unilateral impactions. Fifty –two canines were divided in two groups: group A: included impacted canines causing resorption to neighboring teeth and group B: impacted canines not causing resorption. Canine axis inclination, horizontal cusp location and distance to nearest adjacent tooth were recorded. T-tests (paired, student) determined the significance (P≤0.05) performed to evaluate the effect of resorption within and between each group. Results: Twenty–one canines caused resorption (40%) of the lateral incisor while there were 31 canines not causing resorption. Palatally impacted canines causing resorption to the adjacent teeth showed higher inclination of their axis to the midsagittal plane. Conclusions: Palatally impacted canines have high chance of causing resorption to adjacent teeth. As the canine is more medially located there is an increased chance of resorption especially when the cusp of the maxillary canine was positioned medially to the long axis of the lateral incisor. Highly significant correlation between palatally impacted canines in contact with neighboring teeth and resorption was found.