Introduction: Cleft palates are among the commonest
craniofacial abnormalities. Cleft palate repair is not free of
complications. The formation of a fistula is the most common
complication of palatoplasty.
Aim of Work: To rectify the benefit of using human fibrin
glue as a catalyst in primary palatoplasty and its effect on
lowering the development of postoperative complications.
Methods: Primary palatoplasty was performed for twenty
patients by double flap palatoplasty with human fibrin glue
as a catalyst in the reform from January 2019 to June 2019.
Fibrin glue was prepared from fresh frozen plasma to obtain
thrombin and cryoprecipitate to obtain fibrinogen. Then was
injected between the two palatal flaps and at the suture line
as well.
Results: Out of twenty patients, 5 cases (25%) showed
post-operative complications. Two cases (10%) were complicated
by oronasal palatal fistula one of them (5%) were small
(2mm) at the intersection of soft and hard palate without any
nasal regurgitation and closed spontaneously within two
months of post-operative follow-up. The other one (5%)
continued for further surgical repair, and it also had early
wound infection. Two cases (10%) were complicated by upper
airway obstruction, and one patient (5%) was complicated by
hemorrhage.
Conclusions: The rate of occurrence of complications
was less than in other studies that did the same procedure
without the utilization of fibrin glue in the repair. More
research with more patients and a more extended period of
follow-up is recommended.