Background: Post burn scarring is a common complication
that can lead to functional disability and cosmetic disfigurement.
Superficial burn wounds usually heal without complications,
unlike deep ones that have an increased risk for
abnormal scar formation.
Aim of Study: Is to compare between autologous nanofat
grafting and fractional CO2 laser in the management of post
burn scars regarding aesthetic improvement.
Patients and Methods: This is a prospective study carried
out at Plastic Surgery Department, Ain Shams University
Hospital from February 2020 to February 2022. The study
included 20 cases of post burn scars, they were divided
randomly into two equal groups; the first group was managed
by 2 sessions of autologous nanofat grafting while the other
group was managed by 6 sessions of fractional CO2 laser.
Results: There was statistically significant improvement
after nanofat grafting and fractional CO2 laser. According to
VSS; more statistically significant improvement of pliability
was found among nanofat grafting group than fractional CO2
laser. While POSAS observer scale showed more improvement
for pigmentation and pliability scores. Moreover, POSAS
patient scale found more improvement among nanofat grafting
group regarding itching, color, stiffness and total scores.
Conclusion: Autologous nanofat injection and fractional
CO2 laser use resulted in a significant aesthetic improvement
of post burn scars. However, autologous nanofat injection
had more significant improvement than laser regarding pliability,
pigmentation, itching, color and stiffness.