Major burn injury management represents a difficult issue
especially in developing countries. Skin auto-grafts is the best
natural skin substitute for replacing burned skin but its rarity
in major burns patients stand as an obstacle to be used. Early
deep burn wounds excision and coverage of wounds more
than 30% of body surface area is the main strategy for wound
management in massive burns yet with the absence of skin
banks (skin allo-grafts) and expensive artificial skin substitute's
coverage of raw wounds by these methods is not applicable
in Egypt. In this study, we try to evaluate the benefits to use
both minimal sheets of auto-grafts covered by enough sheets
of allo-grafts to cover all raw area after excision. Using fresh
skin allo-grafts obtained from 1st degree relative of patients
as natural skin substitute. The auto-grafts are meshed 1 to 6
and fixed directly on raw areas while allo-grafts are meshed
1 to 2 and cover both auto-grafts and raw areas, noting that
allo-grafts considered as temporary skin. Follow-up the clinical
changing of these grafts and histopathologically analysis. Out
of the 30 patients 8 had died, 10 patients needed other operations
while 12 had healed with no more procedures.