Neurofibromatosis type 1 (NF-1) is an autosomal dominant
disease that result in vast tumor formation. Craniofacial
Neurofibromatosis is rare condition and it commonly affects
the orbitotemporal midface, nose, upper lip, cheek and neck
with a profound impact on the overall aesthetic outcomes in
these patients. Surgical interventions is the gold standard
treatment of neurofibroma. It is always complex and challenging
due to the variability of the number, site, size, progress
and recurrence are unpredictable. The aim of this study to
present our novel technique using proline mesh for simultaneous
excision and tissue suspension. It is a retrospective
study reviewed 17 patients with craniofacial NF-1. Patients
with intracranial extension and needed neurosurgical intervention
were excluded. Objective and subjective analysis was
done using the Mimics software and the need for additional
surgery “NAS" score scale. Results shown that using the
proline mesh to suspend the tissue hand on hand with NF1
tumor excision is of utmost importance, showing reliable long
term satisfactory aesthetic outcome.