Background: Cicatricial alopecia is a group of disorders
that destroy hair follicles which are replaced with fibrosis,
causing permanent hair loss. Cicatricial alopecias are subdivided
into two groups “primary" and “secondary". For management
of 2ry cases, there are different strategies which
differ with the location, size and other scarred area characteristics.
These strategies include certain surgical procedures
such as excision, flap surgery, use of tissue expansion, and
hair transplantation that gained popularity as a permanent
method for restoring hair loss. In cicatricial alopecia cases,
hair transplant is considered challenging because of the
degenerative changes and decreased vascularity of these areas
that may produce a lower survival rate of donor hair.
Aim of Study: This study aimed to evaluate the role of
PRP and nanofat injections together with follicular unit
extraction technique in restoration of hair in secondary cicatricial
alopecia.
Material and Methods: This study was conducted on 30
patients with secondary cicatricial alopecia. Patients were
divided into 3 groups, 10 patients in each. Group A: Received
PRP with hair transplantation, group B: Received nanofat
injections with hair transplantation, while in group C (Control
group) patients underwent hair transplantation only.
Results: Although adding PRP or nanofat injections with
hair transplantation procedure provides an excellent improvement
in the texture and quality of the scarred tissues compared
to other cases underwent without, there were no significant
differences in the clinical outcomes of hair restoration including
hair growth density.