103268

Effect of Pomegranate Juice against High Fat Diet Induced Fatty Liver in rats

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Last updated: 04 Jan 2025

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Abstract

This research aims at studying the effect of pomegranate juice against high fat diet induced fatty liver in rats. Forty adult male rats Sprague-Dawley strain, were divided into four groups of ten rats each weighing 180±20g. (G1) control group that were fed on standard diet, (G2) rats fed on standard diet with Pomegranate juice (20 ml/kg body weight orally) , (G3) rats fed on high fat diet, (G4) rats fed on high fat diet with pomegranate juice (20 ml/kg body weight orally). The experiment was conducted for 6 weeks. The incidence of fatty liver was evaluated by assayed the liver enzymes in serum (alanine aminotransferase and aspartate aminotransferase), serum lipid profile such as total cholesterol , high density lipoprotein cholesterol, triglycerides and histopathological examination of liver.The high fat diet group (G3), revealed hyperlipidemia, elevated in liver enzymes and histological changes in the liver tissue. While, the rats fed high fat diet with pomegranate juice group (G4), showed reduction in the levels of serum lipids and improvement in the liver enzymes. Furthermore, pomegranate juice reduced the occurrence of histological changes in rat's liver . The results of the study concluded that daily administration of pomegranate juice can protect against developing changes caused by high fat diet and reduced the development of fatty liver. These findings suggested that drinking pomegranate juice may be beneficial for people who are exposed to fatty liver or hypercholesterolemia.
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DOI

10.21608/sjseas.2020.103268

Keywords

Keywords: pomegranate juice, Fatty Liver, High fat diet, Rats

Authors

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سها

Last Name

محمد يوسف

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Affiliation

قسم التغذية وعلوم الأطعمة ، قسم الاقتصاد المنزلي ، کلية التربية النوعية ، جامعة الفيوم ، مصر.

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Volume

2

Article Issue

4

Related Issue

15509

Issue Date

2019-10-01

Receive Date

2020-07-16

Publish Date

2019-10-01

Page Start

179

Page End

192

Print ISSN

2682-3101

Online ISSN

2682-311X

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https://sjseas.journals.ekb.eg/article_103268.html

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https://sjseas.journals.ekb.eg/service?article_code=103268

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6

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المقالة الأصلية

Type Code

1,108

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Journal

Publication Title

المجلة العلمية للتربية النوعية والعلوم التطبيقية

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https://sjseas.journals.ekb.eg/

MainTitle

Effect of Pomegranate Juice against High Fat Diet Induced Fatty Liver in rats

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Article

Created At

22 Jan 2023