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230599

Protective and therapeutic effect of myrrh herb (Commiphora molmol) on inhibited immune system in experimental rats

Article

Last updated: 25 Dec 2024

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Abstract

The present work aimed to study the therapeutic and protective effect of feeding myrrh against immunity inhibition causative to male rats. Forty eight rats were used in this study. They were divided into 8 groups, each one of 6 rats, the first group was the (-ve) control, the second group was left as a (+ve) control group. Groups (3, 4 & 5) were induced immunity inhibition for them at the end of experiment and received myrrh with (50, 100 & 150) mg/kg, respectively for four weeks. Groups (6, 7 & 8) were induced immunity inhibition for them at the beginning of the experiment and received myrrh with (50, 100 & 150) mg/kg, respectively for four weeks. Results revealed that rats in the protective groups (3, 4 and 5), or therapeutic groups (6, 7 and 8) showed significant increased values in levels of their immunity protein (IgG) when compared with untreated rats (+ve group 2). Lymphocytes, total protein and albumin also increased significantly compared to untreated rats (+ve group 2), while their globulin, creatinine, total bilirubin, GPT, GOT and erythrocytes were significantly decreasing compared to control negative group. Group 5 (protective) that had myrrh (150mg/kg) showed highly increase in its immune efficiency. The histopathological examinations of thymus gland and spleen showed relatively no alteration in their structure in rats that were received myrrh at the beginning of the experiment before induced immunity inhibition to them. In conclusion myrrh can be used to increase the protective and therapeutic effect for immunity disorders, and to protect the body and raise its immune efficiency n rats.

DOI

10.21608/ajbs.2022.230599

Keywords

Immune system - Myrrh-IgG- histopathological structure, Thymus gland, spleen, Rats

Authors

First Name

Soha

Last Name

Ibrahim

MiddleName

M

Affiliation

Food Industries Department, Faculty of Agriculture, Ain Shams University

Email

-

City

-

Orcid

-

First Name

Ekbal M

Last Name

Mohamed

MiddleName

-

Affiliation

Home Economics Department, Faculty of Specific Education, Ain, Shams University

Email

-

City

Cairo

Orcid

-

First Name

El-Sayeda

Last Name

El-Sahar

MiddleName

G. E.

Affiliation

Home Economics Department, Faculty of Specific Education, Ain, Shams University

Email

-

City

Cairo

Orcid

-

First Name

Hala

Last Name

Ataya

MiddleName

R

Affiliation

Home Economics Department, Faculty of Specific Education, Ain, Shams University

Email

drhalarashed@sedu.asu.edu.eg

City

Cairo

Orcid

1111-1111-1111-1111

Volume

18

Article Issue

1

Related Issue

32997

Issue Date

2022-06-01

Receive Date

2022-01-12

Publish Date

2022-06-01

Page Start

1

Page End

14

Print ISSN

1687-4870

Online ISSN

2314-5501

Link

https://ajbs.journals.ekb.eg/article_230599.html

Detail API

https://ajbs.journals.ekb.eg/service?article_code=230599

Order

1

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Original Article

Type Code

1,101

Publication Type

Journal

Publication Title

African Journal of Biological Sciences

Publication Link

https://ajbs.journals.ekb.eg/

MainTitle

Protective and therapeutic effect of myrrh herb (Commiphora molmol) on inhibited immune system in experimental rats

Details

Type

Article

Created At

22 Jan 2023